[pSer139]Histone H2AX monoclonal antibody (9F3)

Description:
The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The core histones form an octamer, which is made up of one H3-H4 tetramer and two H2A-H2B dimers. The N-terminal tail of core histones undergoes different post-transcriptional modifications including acetylation, phosphorylation, methylation and ubiquitination. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Western blot analysis of [pSer139] Histone H2AX, mAb (9F3) : Lane 1: MW marker; Lane 2: Jurkat cell lysate; Lane 3: Jurkat cell lysate treated with staurosporine; Lane 4: 3T3 cell lysate; Lane 5: CHO-K1 cell lysate; Lane 6: Rat-2 cell lysate. Western blot analysis of [pSer139] Histone H2AX, mAb (9F3) : Lane 1: MW marker; Lane 2: Jurkat cell lysate; Lane 3: Jurkat cell lysate treated with staurosporine; Lane 4: 3T3 cell lysate; Lane 5: CHO-K1 cell lysate; Lane 6: Rat-2 cell lysate.{{1771691-34-9} medchemexpress|{1771691-34-9} Purity & Documentation|{1771691-34-9} Description|{1771691-34-9} custom synthesis}