Product Name: Anti-APAF1 Antibody
Description: Rabbit IgG polyclonal antibody for Apoptotic protease-activating factor 1(APAF1) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
Host: Rabbit
Isotype: N/A
Validate Species: Human, Mouse, Rat
Clonality: Polyclonal
Form: Lyophilized
Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.carrier free antibody available upon request.
CAS NO: 113906-27-7
Product: PNU-74654
Concentration: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Purification: Immunogen affinity purified.
Molecular Weight: 141840 MW
Protein Function: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. .
Alternative Names: Apoptotic protease-activating factor 1;APAF-1;APAF1;KIAA0413;