Down of Bak, but not Bax, demonstrating that LY2603618 induces Bak-dependent
Down of Bak, but not Bax, demonstrating that LY2603618 induces Bak-dependent intrinsic apoptosis in AML cells (Figure 2D and 2E).rEsuLtsLY2603618 has antileukemic activity against primary AML patient samples and AML…