Product Name :
TAMRA-PEG4-Alkyne
Description:
TAMRA-PEG4-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1225057-68-0
Molecular Weight:
643.73
Formula:
C36H41N3O8
Chemical Name:
2-[6-(dimethylamino)-3-(dimethyliminiumyl)-3H-xanthen-9-yl]-5-[(3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamoyl]benzoate
Smiles :
CN(C)C1=CC2OC3=CC(C=CC3=C(C3=CC=C(C=C3C([O-])=O)C(=O)NCCOCCOCCOCCOCC#C)C=2C=C1)=[N+](C)C
InChiKey:
WQEIEHQRZQLUSE-UHFFFAOYSA-N
InChi :
InChI=1S/C36H41N3O8/c1-6-14-43-16-18-45-20-21-46-19-17-44-15-13-37-35(40)25-7-10-28(31(22-25)36(41)42)34-29-11-8-26(38(2)3)23-32(29)47-33-24-27(39(4)5)9-12-30(33)34/h1,7-12,22-24H,13-21H2,2-5H3,(H-,37,40,41,42)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{P7C3} web|{P7C3} Immunology/Inflammation|{P7C3} Technical Information|{P7C3} In Vivo|{P7C3} custom synthesis}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Pibrentasvir} site|{Pibrentasvir} HCV|{Pibrentasvir} Protocol|{Pibrentasvir} Purity|{Pibrentasvir} custom synthesis|{Pibrentasvir} Autophagy}
Additional information:
TAMRA-PEG4-Alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1225057-68-0|Molecular Weight: 643.73|Formula: C36H41N3O8|Chemical Name: 2-[6-(dimethylamino)-3-(dimethyliminiumyl)-3H-xanthen-9-yl]-5-[(3,6,9,12-tetraoxapentadec-14-yn-1-yl)carbamoyl]benzoate|Smiles: CN(C)C1=CC2OC3=CC(C=CC3=C(C3=CC=C(C=C3C([O-])=O)C(=O)NCCOCCOCCOCCOCC#C)C=2C=C1)=[N+](C)C|InChiKey: WQEIEHQRZQLUSE-UHFFFAOYSA-N|InChi: InChI=1S/C36H41N3O8/c1-6-14-43-16-18-45-20-21-46-19-17-44-15-13-37-35(40)25-7-10-28(31(22-25)36(41)42)34-29-11-8-26(38(2)3)23-32(29)47-33-24-27(39(4)5)9-12-30(33)34/h1,7-12,22-24H,13-21H2,2-5H3,(H-,37,40,41,42)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33345697 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|