In the current study, we found that palmitate considerably upregulates SeP expression in HepG2 hepatocytes, ensuing in IR whilst knock-down of SeP by siRNA reverses these improvements
Next, we evaluated no matter if salsalate was able of stopping palmitate-induced SeP in hepatocytes through the AMPK-dependent FOXO1a pathway. Constant with past stories, palmitate dephosphorylated FOXO1a. Even so, salsalate…