Ples were 10 . The detection limits of Cr, Mn, Ni, Cu, Zn, Cd and Pb were 0.4, 0.02, 0.3, 0.six, two.0, 0.03 and 2.0 mg/kg, respectively. To make sure the reliability and high-quality of 0.02, 0.three, 0.6, 2.0, 0.03 and 2.0 mg/kg, respectively. To ensure the reliability and good quality of your information, normal reference soil (GBW07408) was purchased from the Center of National the information, standard reference soil (GBW07408) was purchased from the Center of National Reference Supplies of China. Recovery values, ranging from 90 to 108 . All observed Reference Materials of China. Recovery values, rangingdeviations (RSD) were decrease than benefits had been corrected with blanks. The relative normal from 90 to 108 . All observed final results 10 . had been corrected with blanks. The relative regular deviations (RSD) have been lower than ten . 2.3. Evaluation Approach of Heavy Metals two.3. Evaluation Method of Heavy Metals 2.three.1. Pollution Evaluation two.three.1.PI, NIPI, PLI and Igeo [346] have been chosen to assess the pollution degree of heavy metals Pollution Evaluation in Handan soil. PIand Igeo [346] had been selected to assess the pollutionsingleof heavy metals PI, NIPI, PLI and Igeo are generally utilized to assess the pollution of a level pollutant. NIPI and PLI were applied to Igeo are generally employed to assess the pollution several pollutant. The in Handan soil. PI andevaluate the extensive pollution ofof a singlepollutants. NIPI calculation method to evaluate the and PLI have been employed is as follows: comprehensive pollution of numerous pollutants. The C calculation technique is as follows: PIi = i (1) C0 Igeoi = log2 PIi 1.5 (2)Appl. Sci. 2021, 11,4 ofN IPI = PLIn = PLIzone =n i( PIi )max 2 + PIi(three) (4) (5)PI1 PI2 PI3 PIiPLI1 PLI2 PLI3 PLInwhere PIi represents pollution index of ith metal. Ci and C0 (mg/kg) stand for the content of ith metal and its background value. The background values refer towards the background values of soil elements in China [37]. (PIi )max represents the maximum PIi . Igeoi stands for the geo-accumulation index of ith metal. NIPI represents the Nemerow integrated pollution index. PLIn stands for the pollution load index in the nth sampling website. PLIzone represents the pollution load index across the study location. two.3.2. Ecological Danger Evaluation Method The calculation technique on the prospective ecological danger index (PERI) is as follows [38]: RI =i =Ei = Ti PIii =nn(6)where RI is the pollutants’ total ecological danger, Ei represents the ecological threat of ith metal, Ti denotes the toxic response factor [34]. The toxic response element of Cr, Mn, Ni, Cu, Zn, Cd and Pb have been two, 1, 5, 5, 1, 30 and five, respectively. The classification regular of PI, Igeo , PLI, NIPI, and PERI is p-Dimethylaminobenzaldehyde Protocol revealed in Table S1 [8]. 2.3.three. Wellness Threat Evaluation Method The caluclation of your overall health threat is as follows: ADDing = C ADDdermal = C IngR EF ED 10-6 EBW AT (7) (8) (9) (10) (11)SA AF ABS EF ED 10-6 EBW AT InhR EF ED PEF EBW AT ADDi R f DiDifenoconazole web ADDinh = C HI =HQi =CR =ADDi SFiwhere ADDing , ADDdermal , and ADDinh would be the imply each day exposure dose to ingestion, dermal and inhalation absorption from soil heavy metals (mg/kg/d) [8]. C stands for the content of metal in soil (mg/kg). A detailed description on the other parameters may be identified in Tables S2 and S3. HQi represents the non-carcinogenic risk of ith heavy metal, when HI stands for the total non-carcinogenic threat [39]. When HI or HQ 1, the risk is little or negligible. When HI or HQ 1, the metal may possess a non-carcinogenic danger. CR represents carcinogenic danger.