Nd 3 months immediately after switching drugs. P 0.001, P = 0.006 when compared with the baseline
Nd 3 months just after switching drugs. P 0.001, P = 0.006 compared to the baseline by Wilcoxon signed rank test.Investigation and Reports in Urology 2013:submit your manuscript | dovepressDovepressTable 2 Adjustments in IPSS and QOL scores from baseline to 3 months, based on seasonal periodJanuary pril 29 74.6 8.6 1.three 1.41.3 1.five 1.7 1.51.eight 1.four 1.0 1.51.2 1.6 1.3 1.31.four 1.7 two.1 1.61.eight 1.8 0.7 1.41.0 1.5 two.five 1.12.4 1.1 three.9 3.54.0 four.two 5.five two.85.six three.1 10.7 6.510.9 7.8 three.2 1.33.1 1.4 10.four six.69.4 six.4b 3.0 1.42.9 1.3 ten.9 6.49.1 6.0 two.7 1.52.4 0.9 13.0 7.113.5 7.three three.1 1.03.1 1.2 five.4 3.14.five 2.5d 5.two 2.94.three 2.9b 6.1 three.86.3 three.8 six.1 two.76.0 2.9 11.7 four.412.0 5.four three.1 1.33.0 1.4 5.five 3.35.six 3.3 11.7 7.812.9 8.0 three.two 1.32.eight 1.five 1.2 1.41.2 1.4 1.eight 1.31.six 1.0 1.1 1.41.two 1.7 1.three 1.51.0 1.3b 1.9 1.61.7 1.eight 0.9 1.50.8 1.3 two.3 1.21.9 1.1d 3.8 three.73.7 three.7 1.four 1.51.two 1.1 1.8 1.41.4 1.3 1.2 1.30.9 1.1 1.three 1.31.two 1.4 two.1 1.41.eight 1.5 1.0 1.21.0 1.four two.1 1.01.7 0.9c four.3 2.93.7 three.4 1.6 1.61.three 1.6 two.4 1.72.four 1.5 1.six 1.51.9 1.five 1.three 1.51.7 1.7 2.six 1.82.5 1.9 1.1 1.31.five 1.5 2.3 1.42.2 1.three five.3 3.55.9 4.three 1.six 1.31.2 1.2 two.3 1.12.2 1.three 1.0 1.11.3 1.five 1.7 1.51.eight 1.five two.1 1.12.six 1.six 0.9 1.11.0 1.three two.1 1.02.0 1.1 4.0 two.14.9 three.4 1.four 1.31.9 1.6b 1.eight 1.61.9 1.four 1.5 1.51.7 1.7 1.four 1.61.4 1.6 2.0 1.62.four 1.9 1.4 1.61.4 1.five 2.3 1.12.two 1.three four.9 four.15.5 4.five 76 73.2 7.two 23 76.0 8.three 29 73.six 8.three 23 76.0 9.1 23 75.0 eight.eight February ay March une April uly May ugust June eptember July ctober 12 73.3 six.7 1.0 1.01.7 1.2b 1.8 1.61.4 1.two 1.4 two.01.7 1.9 0.8 0.71.3 1.4 1.9 1.71.8 1.eight 1.0 1.60.8 1.five 1.8 0.92.1 1.two 4.3 four.74.three four.2 4.5 2.34.7 2.six 9.six 7.910.five 7.1 two.8 1.32.four 1.0 1 2 3 4 5 0 five n=2 10 n = 29 15 n = 12 n = 76 20 n = 23Morita et alSeasonal period from baseline to three monthsDecember archDovepresssubmit your manuscript | dovepress2 79.5 5.1.0 0.00.0 0.0a 3.0 two.81.5 0.7 4.0 1.42.5 three.5 2.0 1.41.0 1.4 three.5 two.15.0 0.0 two.5 three.52.5 three.5 three.0 1.42.5 2.1 10.0 7.110.0 7.Individuals (n) Age (years) IPSS products Q1 incomplete emptying Q2 daytime frequency Q3 intermittency Q4 PPARĪ³ Gene ID urgency Q5 weak stream Q6 straining Q7 nighttime frequency P2Y1 Receptor Compound Voiding symptom score (Q2, four, 7) Storage symptom score (Q3, 5, six) Total IPSS QOL score8.0 two.85.0 four.19.0 9.915.0 11.3 3.0 0.03.0 0.Notes: Data are presented as imply common deviation. bScore at baselinescore at three months; cP , 0.05; dP , 0.01; eP , 0.001 compared to the baseline by Wilcoxon signed rank test. Abbreviations: IPSS, International Prostate Symptom Score; Q, question; QOL, good quality of life.Variety of parameters with substantial changeInvolvement of ambient temperature in nonspecific effect-2 n = 23 n = 29-n =Average month-to-month ambient temperature at 3 months ( )DovepressFigure three Association amongst quantity of parameters with considerable modify and typical month-to-month ambient temperature at three months. Notes: The number of parameters with substantial transform shown in Table 2 was not associated with average month-to-month ambient temperature at 3 months (Figure 1) in every period by Spearman rank correlations (n = 217). For the statistical evaluation, one significantly enhanced parameter was assigned as 1 although 1 drastically deteriorated parameter was assigned as -1.We analyzed the association in between the number of parameters with considerable transform (Table 2) as well as the average monthly ambient temperature at three months (Figure 1) in each seasonal period to examine the possible involvement of ambient temperature within the nonspecific effect within the perceived placebo effect right after switching drugs. For the statistical.